Endocrine Abstracts

Interspecies transmission of prion diseases both centrally and peripherally is associated with longer incubation periods and lower effective titres to within species transmission, a phenomenon called the 'species barrier'. Research into interspecies transmission and disease pathogenesis is crucial for understanding disease risk for vCJD, which has been persistently linked to BSE. Host genetics, transmission route and strain of infective agent have generally been shown to affec...